I just sent the following information to a journalist: Depression, depression aggravated, anxiety, aggressive tendencies, mood alterations, psychotic symptoms, and very rarely, suicidal ideation, suicide attempts and suicide have been reported in patients treated with isotretinoin see section 4. I had a long fight to get Roaccutane, it took me until age 28. If you have any suggestions, please let me know. My dose was 20mg a day and I was 230lb due to being a bodybuilder at that point. I do however know of others who have taken it and not had any issues, but that is 10's of people nothing statistically high enough to extrapolate anything substantial. I totally agree with your comments.
I only wish more doctors would get involved in the discussion. The other did not do this. I fully understand my positive experience doesn't mean everyone is so lucky. I think my main issue is the reporting. I'm not suggesting your view is any less valid than mine.
I was left on anti-biotics for acne for years which did nothing. I know the drug isotretinoin works well for some people but for those who suffer long term depression or worse, we have to be sure they have made an informed choice and are aware of early signs of mental changes. I fully appreciate your view and your experience Peter. Discontinuation of treatment may be insufficient and further evaluation may be necessary. Every death, every suicide, every depressed young person is a tragedy and I appreciate your concern. . Once again, thank you for having the integrity to publish opposing opinions, thank you for the extra info and most importantly thank you for the work you do on all medications.
Whilst I appreciate your views, you need to consider the poor young and older people who suffer with acne. He agreed to speak at our conference as several other medical people did. However, discontinuation of isotretinoin may be insufficient to alleviate symptoms and therefore further psychiatric or psychological evaluation may be necessary. In 38 cases, people died and 25 of those were suicide. My own personal experience is that Roaccutane improved my mental health because it took away one issue which was severely bothering me.
My aim always has been for discussion and sharing information. However, discontinuation of isotretinoin may be insufficient to alleviate symptoms and therefore further psychiatric or psychological evaluation may be necessary and Prof David Healy explain how this is done! I'm currently on medication for unrelated health issues with significant side effects. So what is needed is a genetic type test to find who can safely take this. Sadly most of the medical conference, unlike ours, are funded by the pharmaceutical industry and no such free discussions occur. All drugs have a huge side effect profile, but very few take medicines for no reason and for many they do help. Particular care needs to be taken in patients with a history of depression and all patients should be monitored for signs of depression and referred for appropriate treatment if necessary. People were impressed that Medical Professionals were willing to listen and understand.
A pharmacist told me he thought it was more often a second course of the drug that led to problems. I know my audience would enjoy your work. The side effects are awful not to mention memory issues. So it is vital the people who prescribe isotretinoin do monitor the patients very carefully. One had been fine on the drug and the other collapsed and nearly died. Naturally my heart goes out to anyone who has been adversely affected by any medicine, whether that be short term side effects right up to fatal consequences.
He stated I would not be prescribed it because my acne wasn't bad enough, which I found bizarre. Product information for Roaccutane has been amended to strengthen warnings about depression and the possibility of suicide. I am actually a twin, my twin brother also had acne lasting into his thirties but he didn't go down the Roaccutane route. One being gabapentin, I am having facet joint injections in my back on Friday with the hope of relieving pain so I can stop gabapentin which is one drug I don't wish to continue. Particular care needs to be taken in patients with a history of depression and all patients should be monitored for signs of depression and referred for appropriate treatment if necessary. During the meetings we had with the professor, I also met two dermatologists, one made sure to monitor patients on a weekly basis for mood changes etc. However without full facts you are discriminating and putting false information in the public domain.
For me Roaccutane changed my life. Bereaved father Liam Grant, was determined to take Roche to the High Court over the death of his son, he believed was due to Roaccutane: Patient Warnings and Advice All patients treated with isotretinoin should be observed closely for symptoms of depression or suicidal thoughts, such as sad mood, irritability, acting on dangerous impulses, anger, loss of pleasure or interest in social or sports activities, sleeping too much or too little, changes in weight or appetite, school or work performance going down, or trouble concentrating, or for mood disturbance, psychosis, or aggression. I seriously doubt I could handle 30 or 40mg a day, my lips would have been bleeding every time I opened my mouth. However the pain relief outweighs the huge side effect profile. I always invited the speakers to a dinner the night before so they could interact with the coroner and others who need to speak to each other.
It might be worth looking whether the cases of severe acne are increasing and why. In June last year an expert working group recommended patients be monitored for signs of depression. Pharmaceutical drugs for pain, infections, acne, anxiety, depression, may cause immediate or withdrawal reactions. Superb site you have here but I was curious about if you knew of any user discussion forums that cover the same topics talked about in this article? I definitely appreciate you publishing my somewhat opposing opinions, so thank you. Doctors are advised to monitor patients for signs of depression. Thank you for taking the time to comment. Our mission Roaccutane is a treatment for acne that can cause serious psychiatric side effects, such as depression and suicidal ideation.